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Across clinical trials including studies using up to 4,000mg per day adverse effects are generally mild and uncommon, with gastrointestinal discomfort reported most often.3 11 Because inositol is a naturally occurring compound found throughout the body, safety concerns tend to be less about the ingredient itself and more about formulation quality and unnecessary additions

The question of whether these compounds should be used indefinitely parallels the conversation about blood pressure medications and statins

N., Haigh, W