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When appropriately induced, trained immunity is protective against infection and tumors, and reinforces tissue repair upon acute damage 14,16,17,18,19,20,21 , but its maladaptation leads to chronic inflammatory pathologies and hinders tissue repair after repetitive damage 11,19,22,23,24,25,26,27,28,29

You feel like a different person

You can get infusions purported to fight fatigue, boost your immune system, and plump your skin at IV boutiques

Science 161, 388389

Not a single-target drug that hammers one pathway and creates side effects elsewhere, but multi-mechanism molecules that can address inflammation, barrier repair, and microbial defense at the same time