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Although the iron-overloaded microenvironment can destroy surrounding tissue via ferroptosis and induce inflammatory responses (26), its cytotoxic effects on ectopic endometrial tissue are limited, primarily due to the tissues ferroptosis resistance (10)

Experimental validation Dose response curves and determination of IC 50 values were assessed for the 12 candidate drugs using 3-fold dilution series (see Supplementary Methods (Supplementary File 1) for more details)

Improved Bone Density As we age, bone density decreases, leading to a higher risk of osteoporosis and fractures

However, the study showed that glutamine binds only to ASCT2 [172]

GSH serves as an electron donor to reduce ROS and is oxidized into glutathione disulfide (GSSG)