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459 However, structures of fully metalated, full-length bacterial DtxR/IdeR proteins show the same metal-binding sites and coordination geometry regardless whether a cognate or noncognate metal is used

A recent cost-benefit analysis with at least 5-year follow-up estimated the direct plus indirect costs of ACI to be $16,781, nearly 20% less than that of TKA ($20,568)

Persistent symptoms like fainting, chest pain, or confusion warrant emergency evaluation to identify and treat the underlying cause