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Distribution favors metabolically active organs, particularly the kidneys, liver, stomach wall, and intestinal tissues

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MPGES-1 catalyzes the terminal step of prostaglandin E 2 synthesis through a GSH-dependent isomerization reaction 22

doi:10.3109/10837450.2014.979944 Evidence-Base Disclosure The published evidence base for GHK-Cu consists predominantly of preclinical research animal models (often rats or mice) and in vitro cell-culture experiments