Though L-ascorbic acid is the most potent form of this vitamin, its also the least stable and goes rancid very quickly in skin care products
Notably, GSH binding motif is not conserved among the other seleno-GPxs (GPx2, GPx3, GPx4, and GPx6) justifying their abilities to use wide variety of thiols like cysteine, protein thiols, mercaptoethanol, and dithiothreitol in addition to GSH as reducing equivalent for the catalysis [8, 17, 18]
When critical functions like breathing are slowed too much, overdose occurs
Gradually reduces pigment spots and dark areas
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