Plant GPXLs, containing cysteine in their active site domain, may have dual roles, acting as glutathione peroxidase and thioredoxin peroxidase functions ( 2 O 2 and organic hydroperoxides, as well as their involvement in regulating cellular redox homeostasis by maintaining thiol/disulfide or NADPH/NADP+ ratios ( Deficiency in the activity of either GSH1 or GSH2 impairs GSH production, negatively impacting plant growth and development
GCL comprises a catalytic (GCLC) and a modifier (GCLM) subunit, and its activity can be readily inhibited with DL-buthionine-sulphoximine (BSO) [13]
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Plant Cell 15:12121226 Pavet V, Olmos E, Kiddle G, Mowla S, Kumar S, Antoniw J, Alvarez ME, Foyer CH (2005) Ascorbic acid deficiency activates cell death and disease resistance responses in Arabidopsis
