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doi: 10.1093/brain/123.8.1667 221 WieserG
found that berberine can increase the levels of neuroprotective factors, such as p-AKT and p-CREB, and down-regulate inflammatory response factors to inhibit inflammation, such as NF-B (Zhang et al., 2012)

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In JC virus-infected glioblastoma cells, it is possible to find the same MDR feature