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Mitochondrial dysfunction is also noted to be associated with other ASD-like neurodevelopmental disorders including Down syndrome, DiGeorge syndrome, Rett syndrome, and tuberous sclerosis complex [11,12,13,14]

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4.3 Infertility and erectile dysfunction Smooth muscle plays a critical role in the pathophysiology of infertility and erectile dysfunction (ED), as it is involved in essential physiological processes required for reproductive and sexual function