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J Cereb Blood Flow Metab 1991

Elevation of homocysteine arises from reduced activity of methionine synthase, a vitamin B 12 -dependent enzyme, however, this does not increase GSH biosynthesis

It supports gut microbiome balance in a way that complements BPCs role in digestive wellness

In addition, cotreatment of docetaxel-resistant NSCLC with docetaxel plus R162 inhibited cancer cell growth and metastasis both in vitro and in xenograft mouse models, again suggesting that combination therapy with anticancer drugs plus a GLUD1 inhibitor is an effective cancer treatment 23

The resulting PV2-S71 + PV3-N77 bispecific nanobody (BsNb-ncAA) exhibited higher thermostability and binding affinity compared to the nanobody monomers and the BsNb constructed by simply fusing two proteins