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4 Unique vulnerabilities of teens and young adults 4.1 The developing adolescent brain and cardiovascular system Adolescence is a critical neurodevelopmental period characterized by significant remodeling of brain circuits, particularly those involving the prefrontal cortex and limbic system, which govern executive function, reward processing, and emotional regulation

[8] Animation pioneer "Grim" Natwick (of Fleischers' Betty Boop team) also contributed to the early images of Sonny and Gramps, according to then-contemporaries who collaborated with Natwick

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And to work ceaselessly to forge partnerships with those who can accelerate the change we seek

Bioessays 28 , 11941202 (2006)