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[Abstract]2020 Jun 3;18(2):1559325820929234

During ferroptosis, the antioxidant axis of solute carrier family 7 member 11/glutathione peroxidase 4 (SLC7A11/GPX4) is deactivated, resulting in intracellular oxidative stress

The K i values for each rSmGST inhibitor were determined according to methods described in Nava et al

Clinical use of corticosteroids or non-steroidal anti-inflammatory drugs and adjuvant targeted exercise therapy is common in the conservative treatment of OA

Because of ubiquitination and subsequent proteolysis, Nrf2 turns over rapidly with a half-life of 715 min, which increases to 30100 min in the presence of oxidative or electrophilic stress (McMahon et al