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Clinicians should select the appropriate formulation (e.g., 60 mg immediate-release, 180 mg extended-release, or liquid) based on patient needs

First, diabetes blunts weight loss by roughly 6 to 7 percentage points versus non-diabetic obesity at the same dose, because long-standing high glucose dampens the metabolic cascade the drug works through. Second, the 10-to-15 mg step keeps adding weight loss in every band

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Lithium may cause diseases of the stomach, intestinal tract, central nervous system, and kidneys