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Apart from over 50 known human carcinogens (methylcholanthrene, benzo--pyrenes, acrolein) tobacco smoke contains toxins (carbon monoxide, ammonia, acetone, nicotine, hydroquinone), chemically reactive solids, and oxidants (superoxide, hydrogen peroxide, nitrogen oxides) [87,88]

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However, there was no effect on nicotine intake, metabolism, or saturation

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AND SUICIDAL THOUGHTS AND BEHAVIORS NEUROPSYCHIATRIC REACTIONS IN PATIENTS TAKING BUPROPION FOR SMOKING CESSATION Serious neuropsychiatric reactions have occurred in patients taking ZYBAN for smoking cessation