is glutathione a powerful antioxidant L-Glutathione 1000mg – Antioxidant, Immune Support & Cell Protection – Sowelo What Makes Glutathione So Powerful

42 , e168e185 (2022)

Sarkar M, Brady CW, Fleckenstein J, et al

In mice with lipopolysaccharide (LPS)-induced C57BL/6, luteolin significantly inhibited the NF-B pathway through upregulation of A20 and Nrf2 in microglia and further demonstrated that A20 can exert its function as a downstream factor of Nrf2 [69]

Acknowledgements This work is supported by National Institute of Health [grant number: R01CA166766 (DMW), P41EB013598 (JK)], and UCSF Department of Radiology and Biomedical Imaging internal grants

14 Translational challenges and opportunities The clinical translation of GSH-responsive nanomedicine faces several important barriers