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It interacts with the thymus gland, a key organ in the immune system, to stimulate the production and activation of T-cells and other immune components

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PubMed record Backmund M, Meyer K, Rothenhaeusler HB, Soyka M

[Abstract] Int Immunopharmacol

In both AID patients and corresponding animal models, the expansion and accumulation of MDSCs protect host tissues from damage caused by excessive T cell responses by inhibiting T cell activation and immune reactions (102, 119), This further indicates that MDSCs may exert a detrimental impact on immune responses by modulating the functions of CD4 + and CD8 + T cells, thereby contributing to the pathological processes of AIDs