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The ROS overproduction results in oxidative impairment of lipids, proteins, and DNA (53), where the accumulation of DNA damage induced by ROS may lead to genetic destabilization in the case of cancer, thus facilitating the development of cancer (54)

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The detection of Fusobacterium and other anaerobic taxa in peripheral blood around parturition suggested that intestinal or oral barrier compromise might allow for the systemic dissemination of these microbes, which subsequently colonize the uterus 129