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Accumulated ROS contributes to both sleep deterioration and aging by driving macromolecular damage, including DNA and protein degradation

It is derived from a partial sequence of Body Protection Compound, a protein naturally found in human gastric juice

the further forward they are, the higher the content

Particular emphasis is placed on functionalized COFs for remodeling the immunosuppressive tumor microenvironment, by alleviating hypoxia and depleting glutathione, and their role as core sensitizers in various therapeutic modalities, including photodynamic, sonodynamic, radiotherapy, and chemodynamic therapy, to efficiently trigger immunogenic cell death (ICD)