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Reducing macrophages to improve bone marrow stromal cell survival in the contused spinal cord

A novel cell-penetrating peptide supports hair follicle growth through anti-inflammatory and growth factorassociated mechanisms in preclinical models

S1PR2, located both in the liver and in the brain, activates the ERK and AKT pathways that regulate cell survival, inflammation, and stress response in the CNS

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However, its metabolism places a significant burden on the livers detoxification and antioxidant systems , particularly through depletion of glutathione