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To investigate whether DAM and DAA are associated with neurodegeneration in GCLC-KO mice, we conducted qRT-PCR analyses of DAM and DAA-related genes using cortical samples from 4-month-old GCLC-KO and WT mice (Fig

The supernatants were collected after centrifugation at 10,000 g at 4C for 15 min

A deficiency in B12 can increase susceptibility to infections and cause general fatigue

The concentration of leukotriene D(4) (LTD(4)), which is usually not detectable, was highly increased, whereas LTE(4), the major urinary metabolite in humans, was completely absent

To show the outlines of acinar cells, we used Alexa Fluor 488 conjugated Wheat Germ Agglutinin (1:200) as counterstaining (W11261, Thermo Fisher, Waltham, MA, USA)