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In the cytoplasm, PKM2 can directly associate with the transcription factor c-Myc to create a complex, enhancing the phosphorylation of c-Myc at Thr58 and facilitating its ubiquitination and degradation

Cosmetic benefit of dietary supplements including astaxanthin and tocotrienol on human skin

Increased Energy : Supports mitochondrial function, potentially improving energy levels

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We discuss the molecular mechanisms underpinning hypoxia-driven metabolic adaptations, highlight their implications for tumor progression and therapy resistance, and explore emerging strategies aimed at disrupting these processes to improve cancer treatment outcomes