glutathione disulfide function - an overview Deciphering the mechanism of glutaredoxin-catalyzed

Ayer A, Macdonald P, Stocker R

After pooling the fractions containing pure 3,4- cis -leucocyanidin ( 6 ), MOPSO was added to a final concentration of 10 mM, the pH was set to 6.2 using 5 N NaOH and the pooled fractions were rotary-evaporated to a concentration of 7 mM of 3,4- cis -leucocyanidin ( 6 ), quantified by HPLC-UV (280 nm) with an external calibration curve with 3,4- trans -leucocyanidin ( 14 )

Neuron 39 , 889909 (2003)

NFT-dependent activation of the Nrf2 pathway elevates cellular resilience Nrf2/Keap1 ranks among the most relevant cellular signaling elements that combine sensing of oxidative stress with transcriptional activation of downstream targets involved in antioxidant defense

For IM injections, some protocols start with low doses of 200 mg weekly and gradually increase up to a maximum of 800-1000 mg weekly