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This reduced fatigue resistance in the previous smokers was thought to be at least partly attributable to elevated COHb levels, seen also in the current and other studies 23,47 that not only reduces the oxygen carrying capacity, but also the release of oxygen due to the left-shift of the Hb-dissociation curve 17,24

People with GERD have a small increased risk of developing esophageal cancer over time, according to the American Cancer Society

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