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Altered connectivity in depression: GABA and glutamate neurotransmitter deficits and reversal by novel treatments

Multiple Phase 3 clinical trials in human subjects show sustained weight loss averaging 15-22% of body weight at higher doses, along with major HbA1c reductions, improved glycemic control, visceral fat reduction, and better lipid profiles

A common recommendation is 3-5 IV sessions spread over 2 to 3 weeks for new patients, though that may be overkill for most people

Monitor response and side effects guiding adjustments

Under current federal regulations, dietary supplements do not require FDA approval before being sold