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doi: 10.1210/me.2014-1259 106 HabeggerKMStemmerKChengCMllerTDHeppnerKMOttawayNet al

Compared to healthy individuals, patients with gallstones show significant changes in the composition of their gut microbiota, characterized by an overgrowth of the phylum Proteobacteria [50]

These powerhouse organelles are major sites of oxidative stress due to the high production of reactive oxygen species ROS (reactive oxygen species) and RNS (reactive nitrogen species)

First, it directly neutralises reactive oxygen species the unstable molecules that cause oxidative stress and damage cellular structures over time