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Neurotransmitter Modulation

Parkin is a ubiquitously transcribed protein that has been linked to the endoplasmic reticulum, synaptic vesicles, Golgi apparatus, and mitochondria in intracellular investigations (Shimura et al., 1999

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Molecular studies utilizing siRNA directed against TGH-2 in 3T3-L1 adipocytes demonstrated a 10% decrease in isoproterenol-stimulated glycerol release, while TGH-2 overexpression was found to increase glycerol release by 20%