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For investors, the key question is whether Fit2Win delivers the intended savings without disrupting the smokeless transition that many analysts see as central to the long term story for LSE:BATS

Furthermore, the results of in vitro cell experiments demonstrated that Notch1 overexpression reduces the CSE-induced apoptosis of human pulmonary microvascular endothelial cells (HPMECs), and CSE can significantly activate the extracellular signal-regulated kinase (ERK) signalling pathway

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But there's a second, better test