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An antioxidant is oxidized by transferring electrons to the free radical and preventing other molecules from undergoing oxidation with the free radical

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This numbing effect provides immediate relief that most people notice within minutes of application

10.1186/1471-2482-13-S2-S40 14 BilicM.BumberZ.BlagaicA

Accumulation of GSSG over time spent awake should decelerate glutathione peroxidase activity through product-dependent inhibition and thereby increase NADP+ concentration in the brain (as indeed occurs in sleep deprivation