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It was first isolated from human plasma in 1973 by Loren Pickart, and the tripeptide has since been identified in human saliva and urine

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Now perhaps most importantly for this talk is this experiment, which was done in collaboration with Bruce Ksander and Meredith Ksander at Gregorys Lab, and what we took what we did, you maybe familiar, is you can increase intraocular pressure, IOP, for a month in a mouse by putting these microbeads in this region of the iris, next to the iris