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Trp53 fl/fl (AKP) mice 72 h post-tamoxifen intraperitoneal (i.p.) injection and cultured in 3D as previously reported (Extended Data Fig

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Thrombus formation and the subsequent activation of the coagulation cascade with final generation of fibrin is facilitated by the mCRP-mediated enhancement of tissue factor on the endothelial cell surface, platelet aggregation and thrombus growth (207, 208) (Figure 7)

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