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These include the use of Smoothened (Smo) agonists to activate Shh signaling, as well as small-molecule modulators of intraflagellar transport (IFT) proteins to restore ciliary trafficking and structural integrity [263268]

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Repair proceeds through overlapping phases: hemostasis, inflammation, proliferation (angiogenesis, fibroplasia, matrix deposition), and remodeling (maturation and cross-linking of the matrix)

Antitussive and analgesic effects: Aqueous extract of durian rind can prolong the cough latency period induced by ammonia water and sulfur dioxide in mice, inhibit the number of coughs, and has a good antitussive effect

Retatrutide reduces liver fat through overall metabolic improvement and caloric deficit