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& Foskett, J

Our own earlier reclassification coverage noted that GHK-Cu, Melanotan II, PEG-MGF, LL-37, and dihexa were widely expected to remain in Category 2 because of stronger safety concerns cited at the 2024 advisory committee

Key safety considerations: GLP-1 agonists are contraindicated in personal or family history of medullary thyroid carcinoma, MEN2 syndrome, or pancreatitis

By contrast, for the intravenous (IV) preparation, the UK licence recommends a dose of 4 g/day every 46 h for adults weighing above 50 kg with a dose reduction to 3 g/day in those who have risk of hepatotoxicity

H.HaoQ.KrishnaswamyS.Bekaii-SaabT.Al-RohaimiA.vonMoltke