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Brain 10:28

Looking forward, the clinical application of ferroptosis-based therapies in PDAC hinges on overcoming several pivotal challenges

SAG uses a thioester (S-acyl) bond, which is cleaved specifically by cytoplasmic thioesterases, offering a more targeted intracellular release mechanism with a cleaner safety profile demonstrated in human dosing studies

Moons and Jupiter Imaging Spectrometer (MAJIS) on Jupiter Icy Moons Explorer (JUICE) "Payload JUICE"