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Although known and proposed for more than a decade, phytoremediation of pharmaceuticals is scarcely applied and, until now, only limited data on the ecotoxicological effects of pharmaceutical substances and especially their effects on plants exist

J., Ridker, P

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This means you would need much higher doses to achieve similar effects, making these methods less cost-effective and less reliable

Inhibiting 6-phosphogluconate dehydrogenase reverses doxorubicin resistance in anaplastic thyroid cancer via inhibiting NADPH-dependent metabolic reprogramming