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Assessing cigarette consumption by global report, time-line follow-back, and ecological momentary assessment

Presence of Other Alkaloids: Some research indicates that e-vapor can contain nicotyrine at higher concentrations than cigarette smoke, which may inhibit enzymes that metabolize nicotine, potentially prolonging its effects and complicating direct equivalence calculations

An earlier study came to similar conclusions

Source: CDC It is terrific news for our nations health that the adult cigarette smoking rate fell to a record-low 14 percent in 2017, down from 15.5 percent in 2016 and a remarkable decline of 67 percent since 1965 (when 42.4 percent smoked)