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Sulfonylureas--a novel treatment to reduce tissue damage after acute spinal cord injury

The reduction reaction was catalysed by PDI at room temperature, and the resulting aggregation of reduced insulin B chains was measured at 620 nm

(iv) glutamine polarizes macrophages to M2 phenotype [183] and, as a precursor of glutamate, can also restrain macrophages function, after glutamate-induced N-methyl-D-aspartate receptor (NMDAR) channel activation, leading to tumor development in mouse models of fibrosarcoma and hepatocellular carcinoma [184]

This makes them susceptible to a therapeutic concept known as redox synthetic lethality

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