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Pescosolido N, Gianotti R, Plateroti AM, Pascarella A, Nebbioso M

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Artesunate Studies (114, 115) have found that the antimalarial drug artemisinin analog artesunate (ARS) has strong immunosuppressive activity in RA model, which can inhibit the formation of germinal centers, B cell proliferation and the production of autoantibodies, increase Foxp3 expression, reduce the formation of pannus, and cartilage and bone erosion

Metabolites and ratios of metabolites were considered an autism-associated biomarker if the average performance had a sensitivity of at least 4.5% (indicating a subpopulation of at least 4.5% of the autism study participants that were biomarker-positive) and the proportion of the biomarker-positive (PMP) population of at least 90% autistic individuals (equivalent to the positive predictive value (PPV) of 90% within the CAMP study population prevalence)

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