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In this case, the fact that the P-value for the lackoffit is 0.0964, which is greater than the commonly used threshold of 0.05, suggests that the quadratic model has successfully established a precise functional relationship between the response and the independent variables

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After 72 hours of exposure to the aerosols generated by heat-not-burn devices, both bronchial epithelial cells and smooth muscle cells suffered a loss of viability, and an increase in lactate dehydrogenase release, collagen I and fibronectin, with a detrimental effect on the mitochondrial respiration chain