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Cerebral micro-vessels are able to use both glucose and FAs as energy sources, a process seemingly driven by nutrient availability (Hingorani and Brecher, 1987)

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In metabolic and nutritional regulation, the GH/IGF-1 system responds dynamically to nutrient status and metabolic signals

Furthermore, analytical approaches that rely on administrative boundaries often fail to account for diverse geographical and socio-economic contexts, making meaningful comparisons across areas of varying size and jurisdiction problematic