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To address the need for independent validation, we systematically evaluated all lead variants in publicly available POAG GWAS datasets, including UK Biobank (European ancestry), POAAGG (African ancestry), and other published studies identified through the GWAS Catalog

Long-chain metabolites of vitamin E: metabolic activation as a general concept for lipid-soluble vitamins

In this process, the ubiquitin-proteasome system (UPS), recognized as the principal proteolytic pathway, becomes highly active under pathological conditions such as metabolic muscle atrophy 34

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