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Proteomic analysis further demonstrated that hexokinase 2 (HK2), which catalyzes the first step of glycolysis by converting glucose to glucose-6-phosphate, was significantly downregulated at the protein level (Supplementary Fig

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Over time, this may contribute to: Persistent airway inflammation and altered pulmonary reactivity Digestive disturbance and intestinal permeability Heightened inflammatory sensitivity Neuroinflammatory changes affecting cognition Fatigue related to metabolic strain Increased oxidative stress burden (3) Rather than presenting as a sudden illness, mold toxicity symptoms often progress gradually

RNAi For RNA interference, siRNA duplexes were synthesized in GenePharma