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8 Conclusion Neurodegenerative disorders continue to pose an immense clinical and societal challenge, largely because effective neuroprotective agents fail to reach the brain at sufficient concentrations to exert meaningful therapeutic effects

Investigating two different cohorts (combined n = 3163), it was validated that individuals with high 2PY or 4PY levels have an increased risk of major adverse cardiovascular events

Fischer W, Currais A, Liang Z, Pinto A, Maher P (2019) Old age-associated phenotypic screening for Alzheimers disease drug candidates identifies sterubin as a potent neuroprotective compound from Yerba santa

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