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Kochar et al have described the 5Ms of Geriatrics in Gastroenterology to describe age-friendly care among older adults in gastroenterology

10.1161/circresaha.115.307611 57 HongY.FengJ.DouZ.SunX.HuY.ChenZ.et al (2024)

However, its use was associated with an increased risk of infections and cancer, similar to other biologics, as well as an increase in all cause mortality in patients 50 years and older with at least one CV risk factor (Lee et al, 2014

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Excessive iron accumulation, coupled with its propensity to generate reactive oxygen species (ROS), suggests its potential involvement in various chronic illnesses, including diabetes, neurological disorders, cardiomyopathy, and several human cancers, such as lung cancer, colorectal cancer, and breast cancer (Jiang et al., 2004