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The relative abundance of Erysipelatoclostridium was increased in vehicle-treated mice that underwent the WD to LD switch (WD/LD-V) relative to the two control groups (LD/LD-V and WD/WD-V) but was not increased in 5A-1MQ-treated mice that underwent the same diet switch (WD/LD-T)

In this study, patients with CKD who were in the lower third of homocysteine levels had the same mortality rate as those with normal renal function, while those in the top third of homocysteine levels had a seven-fold mortality risk (van Guldener 2006

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