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doi: 10.1097/QAI.0b013e3181cbdaff 151 Guevara-AguirreJProcelPGuevaraCGuevara-AguirreMRosadoVTeranE
Nat Commun, 2016
Frequently Asked Questions About IGF-1 LR3 1mg IGF-1 LR3 differs from native IGF-1 (70 amino acids) through two modifications: a 13-amino acid N-terminal extension peptide and the substitution of glutamic acid at position 3 with arginine (Glu3 to Arg3, hence 'R3' in the name), resulting in an 83-amino acid protein with a molecular weight of 9,111 Da compared to native IGF-1's 7,649 Da
In this review, we summarize the current existing literatures on NADPH metabolism, including its biological functions, regulatory mechanisms, and the corresponding therapeutic interventions directly or indirectly targeting NADPH metabolism in cancer
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