We do not know whether the effects are sustained long-term
For example, in a 3-week prospective intervention with a high dose of 100 mg riboflavin/day with 70 patients with Crohns Disease, a reduction in systemic oxidative stress (measured by higher free thiol plasma levels), inflammatory markers (IL-2 and C-reactive protein (CRP)) and clinical symptoms of Crohns disease (i.e., a reduction in clinical disease activity index and quality of life improvement) were observed 52
It helps to mop up free radicals produced from exposure to air pollution, toxic chemicals, heavy metals and processed foods, as well as free radicals generated as a result of regular metabolic processes
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