A few studies in humans have been performed with AOD 9604
Comparative Peptide Screening: Frequently included in peptide libraries for screening and comparative compound evaluation
they should not be taken as evidence of equivalent efficacy
5-Amino-1MQ is a first-in-class small molecule inhibitor designed to target Nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme that acts as a master regulator of the cellular "metabolic drain."
Therefore, a bypassing key, i.e., an activated azygos vein as a rescuing pathway, avoiding both the lung and liver and also noted in BuddChiari syndrome (i.e., suprahepatic occlusion of the inferior caval vein) ( BPC 157s endothelial effects and its function as a bypassing key (Sikiric et al., 2018) are strongly supported by its interaction with the nitric oxide (NO) system (for a review, see Sikiric et al., 2014)