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Melanocytes undergo apoptosis and die as a result of H2O2 changing the mitochondria at this concentration

Materials and methods: Wistar rats (3 months old, n = 5/group) were categorized into controls, antioxidant group 1 (vitamin C and vitamin E, VC + VE group), antioxidant group 2 (vitamin C and N-acetylcysteine, VC + NAC group)

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Subsequently, it activated the phosphorylation of VEGFR2, Akt, and eNOS signal pathway without the need for other known ligands or shear stress