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In 1950, the Federal Trade Commission (FTC) investigators had decided that king-size cigarettes, like Embassy, contained "more tobacco and therefore more harmful substances" than are found in an ordinary cigarette

Burns DM, Anderson CM, Gray N

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While the exposure of pulmonary epithelial cells in vitro is less physiologic, most studies show that e-cigarettes increase pro-inflammatory cytokines in epithelial cells in agreement with in vivo data regarding increased MUC5AC production and cytokine induction in the lung

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