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doi: 10.1016/j.immuni.2017.03.019 53 FraternaleAPaolettiMFDominiciSBuondelmonteCCaputoACastaldelloAet al

Over several decades, researchers have documented numerous biological benefits

Proteins and nucleic acids can be damaged by oxidative stress caused by high quantities of reactive oxygen species

90% (GSH), (GSSG)

This finding has direct implications for research protocol design: most published and structured study designs incorporate a rest period following the active phase to allow receptor sensitivity to normalize before any subsequent research cycle, rather than using continuous, uninterrupted administration